Metactive Medical Inc., a Kansas medical device company developing products for the treatment of neurovascular and peripheral vascular diseases, announced today that Kieran Murphy, professor, vice chair and director of research in the department of Medical Imaging at the University of Toronto, presented new nonclinical results from Metactive’s peripheral vascular research program at the Society of Interventional Radiology (SIR) Annual Scientific Meeting.

 According to Metactive President and CEO F. Nicholas Franano, MD, the Blockstent Microcatheter is a peripheral vascular embolization device comprising a 3.3 Fr, highly flexible .014” guidewire-compatible microcatheter delivery system and an inflatable, detachable metallic balloon that delivers immediate, complete, and lasting vessel occlusion.

The research was presented in a poster titled “Comparison of Blockstent Microcatheter with Amplatzer Vascular Plugs and Cook Nester Embolization Coils in Canine Model of Acute and Chronic Arterial Occlusion.” Murphy presented results comparing the use of Metactive’s Blockstent Microcatheter, an over-the-wire embolic device for the occlusion of peripheral arteries and veins, with commercially available vascular plugs and coils to occlude axillary and internal thoracic arteries in a well-accepted model.

Results from the study show that the placement of the Blockstent Microcatheter resulted in immediate and complete occlusion in all eight treatments. At 4-week follow-up, histology showed a mean arterial occlusion of 98 percent. No arteries treated with Amplatzer Vascular Plugs or Nester Coils showed immediate occlusion by angiography.

The average time to achieve complete occlusion was approximately 30 minutes for the Amplatzer Vascular Plugs and approximately 4 minutes for the Nester Coils. At 4-week follow up, arteries treated with the Amplatzer Vascular Plugs showed 57 percent mean occlusion and arteries treated with Nester Coils showed 81 percent mean occlusion, by histology.

“Physicians have long desired a deliverable vascular plug that can be placed with a high degree of accuracy and provides immediate, complete and lasting vessel occlusion with a low risk of migration. These early results support the potential for the Blockstent Microcatheter to meet that need,” Murphy said. VTN

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