The treatment of spider and varicose veins by the injection of sclerosants (sclerotherapy) is not a new development in therapeutics. The modern beginnings of sclerotherapy date back to the invention of the syringe (1831) and the hypodermic needle (1845) but some of the ancient sclerotherapists were reporting their results as early as 1665 when Sigismond Johann Elsholz treated venous ulcers by injecting them with plant extracts using a chicken bone for a needle and the bladder of a pigeon as a syringe! Since then, the treatment of spider and varicose veins has moved into the modern, scientific mainstream as one of the most common therapeutic tools used to treat varicose veins (VV) and spider veins (SV) in the United States and other developed countries.

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